A systematic review of “myokines and metabolic regulation”

Q3 Health Professions Apunts Medicina de l''Esport Pub Date : 2018-10-01 DOI:10.1016/j.apunts.2018.09.003
Henry H. León-Ariza, María P. Mendoza-Navarrete, María I. Maldonado-Arango, Daniel A. Botero-Rosas
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引用次数: 2

Abstract

Bad habits such as sedentary lifestyle, obesity or overfeeding, are related to the production of chronic pro-inflammatory states, the main risk factor for the development of chronic noncommunicable diseases (CNCD). However, modifying only the body weight does not reduce the risk, it is necessary to increase muscle mass, this implies there is a beneficial relationship associated with the muscle tissue that is not fully elucidated. During the last years, the most interesting cellular explanations have focused on the production of muscle cytokines called myokines, among which stand out interleukin 6, the inhibitory factor of leukemia, with others recently studied such as mionectine and muscline. Due to the multiple advances, this intends to present the most recent and representative findings about myokines, correct concepts and demonstrate their applicability in the prescription of physical exercise for health.

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“肌因子与代谢调节”的系统综述
久坐不动的生活方式、肥胖或过度进食等不良习惯与慢性促炎状态的产生有关,而促炎状态是慢性非传染性疾病(CNCD)发展的主要危险因素。然而,仅仅改变体重并不能降低风险,增加肌肉质量是必要的,这意味着与肌肉组织之间的有益关系还没有完全阐明。在过去的几年里,最有趣的细胞解释集中在肌肉细胞因子的产生上,称为肌因子,其中突出的是白细胞介素6,白血病的抑制因子,以及最近研究的其他因子,如mionconnecine和muscline。由于多方面的进展,本文拟介绍关于肌因子的最新和有代表性的发现,正确的概念,并证明其在健康体育运动处方中的适用性。
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来源期刊
Apunts Medicina de l''Esport
Apunts Medicina de l''Esport Health Professions-Physical Therapy, Sports Therapy and Rehabilitation
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