Clinical research of femtosecond laser mushroom incision penetrating corneal transplantation combined cataract extraction

Xueqian Cao, Linnong Wang
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Abstract

Objective To evaluate the effectiveness and safety of mushroom incision femtosecond-assisted penetrating corneal transplantation combined cataract extraction surgery. Methods A retrospective analysis was carried out for 29 patients (30 eyes) who performed FS- PKP combined cataract extracapsular extraction versus 11 patients (11 eyes) who performed traditional PKP combined cataract extracapsular extraction. Lesions involving whole cornea and all the patients’ lenticular opacity were moderate or above. Femtosecond laser was used for make mushroom incision of corneal graft and corresponding recipient bed, conventional group used trephine. Then implemented cataract extracapsular extraction, intraocular lens were implanted, sutured at last. Their follow-up were 1 week, 1 month, 3 months and 6 months, part of the patient were followed up until 18 months. The follow-up results of two groups were compared. Results Postoperative vision of two groups had increased, postoperative UCVA and BCVA of femtosecond group were better than normal group, postoperative astigmatism was lower than normal group within 3 months, and there was no obvious difference after 6 months. No obvious difference was found between two groups of ECD and postoperative complications occurrence rate. Conclusions Mushroom incision of femtosecond-assisted penetrating corneal transplantation combined cataract extraction surgery has obvious curative effect, precision cutting and high security, its early visual acuity is superior to the traditional penetrating keratoplasty, it can be widely used in clinical therapy. Key words: Femtosecond laser; Keratoplasty; Cataract; Penetrating; Leukoma
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飞秒激光蘑菇切口穿透角膜移植联合白内障摘除的临床研究
目的评价蘑菇切口飞秒辅助穿透性角膜移植联合白内障摘出术的有效性和安全性。方法回顾性分析29例(30眼)FS- PKP联合白内障囊外摘出术与11例(11眼)传统PKP联合白内障囊外摘出术的临床资料。病变累及整个角膜,所有患者的晶状体混浊程度均在中度及以上。采用飞秒激光作蘑菇形角膜移植切口及相应的受体床,常规组采用环钻。术后行白内障囊外摘出、人工晶状体植入术、缝合术。随访时间分别为1周、1个月、3个月、6个月,部分患者随访至18个月。比较两组随访结果。结果两组术后视力均有提高,飞秒组术后UCVA、BCVA优于正常组,术后3个月内散光低于正常组,6个月后无明显差异。两组间ECD及术后并发症发生率无明显差异。结论蘑菇切口飞秒辅助穿透性角膜移植联合白内障摘出术疗效明显、切割精确、安全性高,其早期视力优于传统的穿透性角膜移植术,可广泛应用于临床治疗。关键词:飞秒激光;角膜移植术;白内障;渗透;角膜白斑
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期刊介绍: China Practical Ophthalmology was founded in May 1983. It is supervised by the National Health Commission of the People's Republic of China, sponsored by the Chinese Medical Association and China Medical University, and publicly distributed at home and abroad. It is a national-level excellent core academic journal of comprehensive ophthalmology and a series of journals of the Chinese Medical Association. China Practical Ophthalmology aims to guide and improve the theoretical level and actual clinical diagnosis and treatment ability of frontline ophthalmologists in my country. It is characterized by close integration with clinical practice, and timely publishes academic articles and scientific research results with high practical value to clinicians, so that readers can understand and use them, improve the theoretical level and diagnosis and treatment ability of ophthalmologists, help and support their innovative development, and is deeply welcomed and loved by ophthalmologists and readers.
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