Evaluating the Risk of Covid-19 Transmission from Conjunctival and Lacrimal Discharge: A Review

Shalini Sanyal, S. Law
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Abstract

The ocular surface, which is constantly exposed to the external environment, is one of the most sensitive zones and any complications which have a detrimental impact on it leading to re-duced vision and/or blindness, severely impact the quality of life. The most commonly afflicted parts of the eye are the conjunctiva, eyelid, and cornea due to their position. Since the eye is moder-ately susceptible to microbial infection from bacteria, fungi or even viruses;there has been much speculation about whether or not the novel coronavirus-2 (SARS-CoV-2) can lead to ocular disor-ders. Given the high rate of transmission for this disease, it is of great importance to evaluate the risk of disease communication from the eye, such as by conjunctival and/ lacrimal discharge. While there are many articles on the topic exploring the ocular aspect of COVID-19/ SARS-CoV-2 infection;there is a significant volume of data that may or may-not seem contradictory at first glance. This is primarily due to the still-emerging nature of this disease and new data that is being unearthed every day. The problem is compounded by the fact that despite the over-all concordance, the different clinical teams have varying diagnostic criteria. This review attempts to consolidate the data available thus far regarding the risk of COVID-19 transmission from conjunctival/lacrimal discharge apart from the known modes of transmission, thereby allowing us to speculate whether additional protective measures are required to combat the zoonotic coronavirus pandemic currently ravaging the world.
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评估结膜和泪液传播Covid-19的风险:综述
眼表经常暴露在外部环境中,是最敏感的区域之一,任何对其产生不利影响的并发症都会导致视力下降和/或失明,严重影响生活质量。眼睛最常见的受累部位是结膜、眼睑和角膜,因为它们的位置。由于眼睛对细菌、真菌甚至病毒的微生物感染具有中等易感性,因此人们对新型冠状病毒-2 (SARS-CoV-2)是否会导致眼部疾病有很多猜测。鉴于这种疾病的高传播率,评估疾病从眼睛传播的风险非常重要,例如通过结膜和/泪液。虽然有许多文章探讨了COVID-19/ SARS-CoV-2感染的眼部方面,但有大量的数据乍一看可能是矛盾的,也可能不是矛盾的。这主要是由于这种疾病仍在出现,而且每天都有新的数据被挖掘出来。尽管总体上是一致的,但不同的临床小组有不同的诊断标准,这一事实使问题更加复杂。本综述试图整合迄今为止关于结膜/泪液传播COVID-19风险的现有数据,除了已知的传播方式,从而使我们能够推测是否需要采取额外的保护措施来对抗目前肆虐世界的人畜共患冠状病毒大流行。
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