Seborrheic dermatitis: unique possibilities of vitamin therapy

Abstract

In practical dermatology, the problem of seborrheic dermatitis is actively considered as the most common pathological condition among the population Objective — to study the clinical effectiveness and safety of the use of the Natubiotin drug in the treatment of patients with seborrheic dermatitis. Materials and methods. 150 patients with seborrheic dermatitis were included in the study. The control group included 50 healthy people of the same age. The severity of seborrheic dermatitis was determined using a scoring scale that included evaluation of the intensity of erythema, swelling, wetting, excoriations, peeling, and fattiness of the skin. The level of anxiety was estimated according to the Spielberger—Khanin self-esteem scale, the level of neuroticism — according to the diagnostic method of L.I. Wasserman. A survey was also conducted using the Beck scale for self-assessment of the severity of depression. Depending on the method of treatment, patients with seborrheic dermatitis were divided into two groups: I (experimental) — 100 patients who received Natubiotin drug in a dose of 5 mg once a day for 3 months; II (control) — 50 patients who underwent standard therapy. Results and discussion. Additional inclusion of Natubiotin drug in the treatment regimen of seborrheic dermatitis ensured the recovery of 100 % patients with localization of the pathological process on the scalp and face. Only 5.3 % of patients with localization of seborrheic dermatitis on the trunk had slight scaling and fattiness of the skin. After the treatment with the inclusion of Natubiotin drug, the indicators of the point assessment of the severity of seborrheic dermatitis in patients of group I were significantly better than in group II that received standard therapy. The assessment of subjective symptoms such as itching and sleep disturbances were also significantly better after using Natubiotin. Vitamin therapy with biotin contributed to a significant reduction of state anxiety, depression and neuroticism in patients. The obtained data indicate the high effectiveness of Natubiotin for the treatment of seborrheic dermatitis. Conclusions. The course of seborrheic dermatitis is accompanied by high personal and state anxiety, increased neuroticism and tendency to depression. Therapy of seborrheic dermatitis with the use of Natubiotin is justified and appropriate, as it provides a quick and long­lasting clinical effect, normalization of the skin condition and improvement of the psychogenic state of patients. The obtained results give reason to recommend the widespread use of Natubiotin drug for the treatment of seborrheic dermatitis.