Gender peculiarities of critical lower limb ischemia

N. I. Glushkov, P. Puzdriak, A.N. Agurbash, Anatoly V. Razepin, Mikhail A. Ivanov
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Abstract

BACKGROUND: Development of critical ischemia of lower limbs in patients with atherosclerosis causes negative consequences due to the high probability of detecting multilevel changes, as well as identifying coronary and carotid pools. АIM: The aim of the study was to investigate gender differences in critical lower limb ischemia of atherosclerotic genesis following reconstructive interventions. MATERIALS AND METHODS: Arterial reconstructions have been performed in 261 patients with peripheral atherosclerosis (95 women and 166 men). The specific features of reconstructive interventions have been taken into account; complications and the number of amputations have been analyzed in the early period. RESULTS: Higher pulse pressure has been registered in the female group; tibial arteries have been affected significantly more frequently (p 0,05). Thrombosis of the operated segment has been observed more frequently in the male patients at the stage of critical ischemia; in the case of claudication the complications were sporadic. CONCLUSIONS: The best results of reconstructive care in men and women with peripheral atherosclerosis at the claudication stage determine the vector of active tactics in the absence of conservative treatment results.
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危重下肢缺血的性别特征
背景:动脉粥样硬化患者下肢严重缺血的发展,由于检测到多水平变化以及识别冠状动脉和颈动脉池的可能性很大,导致不良后果。АIM:该研究的目的是研究重建干预后动脉粥样硬化发生的严重下肢缺血的性别差异。材料和方法:对261例外周动脉粥样硬化患者(女性95例,男性166例)进行了动脉重建。已考虑到重建措施的具体特点;对早期并发症及截肢人数进行了分析。结果:女性患者脉压增高;胫骨动脉受影响的频率明显高于其他患者(p < 0.05)。手术段血栓形成在男性患者的严重缺血阶段更为常见;在跛行病例中,并发症是偶发的。结论:跛行期男性和女性外周动脉粥样硬化患者的重建治疗的最佳效果决定了在缺乏保守治疗结果的情况下积极策略的载体。
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