2009 H1N1 Influenza Infection: Spectrum Of Chest CT Findings, With Radiologic- Pathologic Correlation

Abstract

The novel influenza A H1N1 virus resulted in the recent influenza pandemic of 2009. In this article, we describe the spectrum of thoracic computed tomography (CT) findings in 8 patients with laboratory-confirmed H1N1 infection. Peribronchovascular and subpleural groundglass opacities and consolidations, pulmonary embolism, and pleural effusions are recently reported findings. Volume loss, bronchial wall thickening, bronchiectasis, mosaic attenuation, and lymphadenopathy are not commonly reported findings. Cryptogenic organizing pneumonia developed as a complication in one of our H1N1 cases, which has not been previously reported. We also describe radiologic-pathologic correlation in an additional case, where autopsy demonstrated diffuse alveolar damage.