{"title":"The role of mitochondria in tumorigenesis","authors":"Mouza Mohammed AlFashti AlAleeli","doi":"10.15761/imm.1000356","DOIUrl":null,"url":null,"abstract":"The maternal inheritance of the mitochondrial DNA is one of its amazing characteristics. It is located in the matrix of a mitochondrion. The cellular organelle that is responsible for the generation of ATPs is the mitochondrion. A lot of studies have linked the mitochondria with the generation of cancer cells. There is a crosstalk in the medical research field that whether the cancer cells were originated from a nuclear defect or from a mitochondrial dysfunction. In this review paper, I will highlight the role of mitochondria in tumorigenesis.","PeriodicalId":94322,"journal":{"name":"Integrative molecular medicine","volume":"28 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Integrative molecular medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/imm.1000356","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The maternal inheritance of the mitochondrial DNA is one of its amazing characteristics. It is located in the matrix of a mitochondrion. The cellular organelle that is responsible for the generation of ATPs is the mitochondrion. A lot of studies have linked the mitochondria with the generation of cancer cells. There is a crosstalk in the medical research field that whether the cancer cells were originated from a nuclear defect or from a mitochondrial dysfunction. In this review paper, I will highlight the role of mitochondria in tumorigenesis.