Study on Effect of Skin Elasticity by Polar Low Molecular Weight Keratin Peptide

Ji-young Maeng, G. Nam
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Abstract

Using Fervidobacterium islandicum AW-1, polar low molecular weight keratin peptides were produced and confirmed through factors related to the skin elasticity. As a result of confirming the cytotoxicity and collagen synthesis ability according to the concentration of the polar low molecular weight keratin peptide in human fibroblasts, it was confirmed that the cytotoxicity did not appear and the collagen synthesis in human fibroblasts was increased. A mask pack containing a polar low-molecular weight keratin peptide was used, and a test product was used for 4 weeks in 22 healthy women subjects. As a result, it showed statistically significant effects on skin elasticity, skin torsion elasticity, skin color and moisture improvement. Through this test, it was confirmed that the polar low-molecular keratin peptide can be used as a cosmetic ingredient that helps improve skin elasticity.
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极性低分子量角蛋白肽对皮肤弹性影响的研究
利用岛铁杆菌AW-1制备极性低分子量角蛋白肽,并通过皮肤弹性相关因素进行验证。根据极性低分子量角蛋白肽在人成纤维细胞中的浓度证实其细胞毒性和胶原合成能力,证实成纤维细胞不出现细胞毒性,胶原合成增加。使用含有极性低分子量角蛋白肽的面膜包,并在22名健康女性受试者中使用了4周的测试产品。结果显示,它对皮肤弹性、皮肤扭转弹性、肤色和改善水分有统计学意义。通过这次试验,证实了极性低分子角蛋白肽可以作为一种有助于提高皮肤弹性的化妆品成分。
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