{"title":"Epistasis and hybrid sterility in Saccharomyces","authors":"D. Greig, R. Borts, E. Louis, M. Travisano","doi":"10.1098/rspb.2002.1989","DOIUrl":null,"url":null,"abstract":"Hybrid sterility is thought to be due to deleterious epistatic interactions between genes from different species. Here we demonstrate that dominant genic incompatibility does not contribute to sterility in hybrids between Saccharomyces cerevisiae and five closely related species. Sterile diploids were made fertile by genome doubling to produce hybrid tetraploids. Based on these and previous results, we conclude that neither genic incompatibility nor classical chromosomal speciation models apply.","PeriodicalId":20585,"journal":{"name":"Proceedings of the Royal Society of London. Series B. Biological Sciences","volume":"21 1","pages":"1167 - 1171"},"PeriodicalIF":0.0000,"publicationDate":"2002-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"100","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Royal Society of London. Series B. Biological Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1098/rspb.2002.1989","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 100
Abstract
Hybrid sterility is thought to be due to deleterious epistatic interactions between genes from different species. Here we demonstrate that dominant genic incompatibility does not contribute to sterility in hybrids between Saccharomyces cerevisiae and five closely related species. Sterile diploids were made fertile by genome doubling to produce hybrid tetraploids. Based on these and previous results, we conclude that neither genic incompatibility nor classical chromosomal speciation models apply.