Screening influencing factors of blood stasis constitution in traditional Chinese medicine

Q3 Medicine Digital Chinese Medicine Pub Date : 2022-06-01 DOI:10.1016/j.dcmed.2022.06.006
Zhou Xiaoying , Yang Shengwen , Ou Jintao , Wang Zhuo , Wang Guangrong , Luo Yue
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Abstract

Objective

To study the influencing factors of blood stasis constitution and provide a basis for treating blood stasis-related diseases by traditional Chinese medicine (TCM) constitution identification.

Methods

Data were collected using the self-developed TCM constitution identification platform based on B/S model by the project team. The obtained data were divided into blood stasis constitution and normal constitution groups. The differences of the categorical type influencing factors (gender, birth mode, feeding mode within four months of birth, family history, marital status, eating habits, sleeping habits, exercise habits, emotional state, stress situation, and living environment) and the quantitative type influencing factors (sleep time, age, and mother's age at birth) on the constitution of the two groups were analyzed. In the single-factor analysis, the Pearson's chi-square test was selected for the categorical variable, and the independent sample t test and Mann-Whitney U nonparametric test were selected for the quantitative variables according to whether they conformed to the positive-terrestrial distribution; the binary logistic stepwise regression method was selected for the multi-factor analysis.

Results

The data of 318 cases were collected from the TCM composition identification platform, and 159 cases of blood stasis constitution were used as the experimental group and 159 cases of normal constitution were used as the control group. The Pearson's chi-square test yielded significant differences (P < 0.05) in the effects of gender, pressure situation, family history, living environment, emotional state, exercise habits, and dietary habits on blood stasis constitution. The independent samples t test yielded differences in sleep duration between the blood stasis constitution and normal constitution populations (P < 0.05), which meant sleep duration of the blood stasis constitution population was less than that of the normal constitution population. The Mann-Whitney U nonparametric test results accepted the original hypothesis that there was no difference in the distribution of age and mother’s age at birth across constitution types (P > 0.05). Binary logistic regression analysis showed that gender, family history, marital status, living environment, exercise habits, and emotional state were risk factors for blood stasis constitution (P < 0.05).

Conclusion

Gender, family history, living environment, emotional state, and exercise habits were significant influencing factors of blood stasis constitution. Blood stasis constitution populations can pay more attention to these influencing factors in their daily life for the prevention and reconciliation of blood stasis constitution.

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中医瘀血体质影响因素的筛选
目的探讨血瘀体质的影响因素,为中医体质鉴定治疗血瘀相关疾病提供依据。方法采用项目组自行开发的基于B/S模式的中药体质识别平台进行数据采集。将所得数据分为血瘀体质组和正常体质组。分析两组儿童的分类型影响因素(性别、出生方式、出生后4个月内的喂养方式、家族史、婚姻状况、饮食习惯、睡眠习惯、运动习惯、情绪状态、应激状况、生活环境)和定量型影响因素(睡眠时间、年龄、母亲出生年龄)对体质的影响差异。单因素分析中,分类变量采用皮尔逊卡方检验,定量变量根据是否符合正大地分布采用独立样本t检验和Mann-Whitney U非参数检验;采用二元logistic逐步回归法进行多因素分析。结果从中药成分鉴定平台收集318例患者资料,其中血瘀体质者159例为实验组,正常体质者159例为对照组。皮尔逊卡方检验显示显著差异(P <性别、压力状况、家族史、生活环境、情绪状态、运动习惯、饮食习惯对血瘀体质的影响0.05)。独立样本t检验显示血瘀体质与正常体质人群的睡眠时间存在差异(P <0.05),说明血瘀体质人群睡眠时间少于正常体质人群。Mann-Whitney U非参数检验结果接受了最初的假设,即不同体质类型的年龄和母亲出生年龄的分布没有差异(P >0.05)。二元logistic回归分析显示,性别、家族史、婚姻状况、生活环境、运动习惯、情绪状态是血瘀体质的危险因素(P <0.05)。结论性别、家族史、生活环境、情绪状态、运动习惯是血瘀体质的重要影响因素。血瘀体质人群在日常生活中可多注意这些影响因素,以预防和调和血瘀体质。
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来源期刊
Digital Chinese Medicine
Digital Chinese Medicine Medicine-Complementary and Alternative Medicine
CiteScore
1.80
自引率
0.00%
发文量
126
审稿时长
63 days
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