Membranoproliferative glomerulonephritis-current understanding

Abstract

Membranoproliferative glomerulonephritis (MPGN) is a heterogeneous entity depicting a similar pattern of glomerular injury secondary to different aetiologies. It is one of the primary glomerular diseases contributing for development of end stage renal disease. There is no definitive treatment of MPGN owing to the lack of understanding the aetiopathogenesis. Over the last decade, there has been publication of enormous literature regarding its pathogenesis, understanding, clinically compatible reclassification and thus a step forward in treatment.