Anemia severa por parvovirus B19 en trasplante renal: reporte de caso y revisión corta

Abstract

We present the case of female patient, aged 19, who developed progressive anemia at 4 weeks of receiving renal allograft, which is accentuated by a change in hemoglobin level from 11.3 to 3.7 g/dl, in anemic syndrome developing is decided transfuse. All routine laboratories were reported as normal except line erythrocyte normochromic normocytic anemia and severe reticulocytopenia which prompted a search of parvovirus B19 and performing a bone marrow aspirate showed pure red cell aplasia. Quantification of viral DNA was reported to > 100,000,000 copies/ml, so she was treated with intravenous gamma globulin for 5 days, which resolved completely without recurrence. At all times the renal function remained normal. As part of the study considering thoracic tomography association with red cell aplasia thymoma, which confirmed the suspect, however, assessing risk/benefit ratio and due to the absence of weakness syndrome or other tracking finding decided paraneoplastic imaging with scheduling of elective thymectomy.