Hypertension and Diabetes Status by Patterns of Stress in Older Adults From the US Health and Retirement Study: A Latent Class Analysis

Jessica Fernandez, F. A. Montiel Ishino, Faustine Williams, N. Slopen, Allana T. Forde
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Abstract

Background Hypertension and diabetes disproportionately affect older non‐Hispanic Black and Hispanic adults in the United States. Chronic stress may partially explain these disparities. This study identified underlying stress profiles of older US adults, analyzed stress profiles in relation to hypertension and diabetes, examined the distribution of stress profiles by race and ethnicity, and assessed patterns of change in latent classes of stress over time. Methods and Results Latent class analysis was conducted with a nationally representative sample of older US adults who completed 3 waves of the HRS (Health and Retirement Study) (ie, 2010 [n=6863], 2014 [n=4995], and 2018 [n=3089]). Latent classes of stress in 2010 (ie, stress profiles) were identified using 15 indicators of unmet needs within 5 categories (ie, physiological, safety/security, belonging, esteem, and self‐fulfillment). Hypertension and diabetes status were examined as outcomes of latent class membership at 3 time points, and race and ethnicity were examined in association with class membership, adjusting for sociodemographic covariates. Finally, a latent transition analysis examined the stability of latent class membership and racial and ethnic differences in the patterns of stress profiles experienced from 2010 to 2018. Five classes were identified: Generally Unmet Needs (13% of sample), Generally Met Needs (42% of sample), Unmet Self‐Efficacy/Goal Needs (12% of sample), Unmet Financial Needs (20% of sample), and Unmet Social Belonging Needs (13% of sample). Compared with the Generally Met Needs class, the Generally Unmet Needs class had higher odds of hypertension (odds ratio [OR], 1.80; [95% CI, 1.35–2.39]) and diabetes (OR, 1.94; [95% CI, 1.45–2.59]), and the Unmet Financial Needs class had higher odds of diabetes (OR, 1.50; [95% CI, 1.10–2.05]). Non‐Hispanic Black participants compared with non‐Hispanic White participants had higher odds of being members of the Generally Unmet Needs, Unmet Self‐Efficacy/Goal Needs, and Unmet Financial Needs classes (OR, 2.70; [95% CI, 1.59–4.58]; OR, 1.99; [95% CI, 1.15–3.43]; and OR, 4.74; [95% CI, 3.32–6.76], respectively). Class membership remained relatively stable over time, with 93% of participants remaining in Generally Met Needs and 78% of participants remaining in Generally Unmet Needs across time points. Compared with non‐Hispanic White participants, non‐Hispanic Black participants had lower odds of Generally Met Needs class membership at any time point (OR, 0.60; [95% CI, 0.42–0.84]) and had lower odds of moving into the Generally Met Needs class and higher odds of moving into the Unmet Financial Needs class from 2010 to 2014 (OR, 0.33; [95% CI, 0.13–0.86]; and OR, 3.02; [95% CI, 1.16–7.87], respectively). Conclusions Underlying classes of stress based on unmet needs were associated with hypertension and diabetes status. Racial and ethnic differences were observed for both latent class membership and transitions between classes over time. Latent classes of stress associated with unmet needs, hypertension, and diabetes and the ability to transition between classes may explain the perpetuation of racial and ethnic disparities in cardiovascular health. Interventions targeting unmet needs may be used to confront these disparities.
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美国健康与退休研究中老年人压力模式对高血压和糖尿病状况的影响:一项潜在分类分析
背景:在美国,高血压和糖尿病不成比例地影响着非西班牙裔黑人和西班牙裔老年人。慢性压力可能部分解释了这些差异。本研究确定了美国老年人的潜在压力概况,分析了与高血压和糖尿病相关的压力概况,检查了压力概况的种族和民族分布,并评估了潜在压力类别随时间的变化模式。方法和结果对完成了三波HRS(健康与退休研究)的美国老年人全国代表性样本(即2010年[n=6863]、2014年[n=4995]和2018年[n=3089])进行了潜在类别分析。2010年的潜在压力类别(即压力概况)使用5类(即生理、安全/保障、归属、尊重和自我实现)中未满足需求的15个指标来确定。在3个时间点检查高血压和糖尿病状况作为潜在阶层成员的结果,并检查种族和民族与阶层成员的关系,调整社会人口学协变量。最后,一项潜在转变分析检验了2010年至2018年潜在阶级成员的稳定性以及种族和民族在压力剖面模式中的差异。确定了五个类别:一般未满足的需求(占样本的13%),一般未满足的需求(占样本的42%),未满足的自我效能/目标需求(占样本的12%),未满足的财务需求(占样本的20%)和未满足的社会归属需求(占样本的13%)。与一般满足需求组相比,一般未满足需求组患高血压的几率更高(比值比[OR], 1.80;[95% CI, 1.35-2.39])和糖尿病(OR, 1.94;[95% CI, 1.45-2.59]),未满足财务需求的人群患糖尿病的几率更高(OR, 1.50;[95% ci, 1.10-2.05])。非西班牙裔黑人参与者与非西班牙裔白人参与者相比,成为“一般未满足需求”、“未满足自我效能/目标需求”和“未满足财务需求”类别成员的几率更高(OR, 2.70;[95% ci, 1.59-4.58];或者,1.99;[95% ci, 1.15-3.43];OR为4.74;[95% CI, 3.32-6.76])。随着时间的推移,班级成员保持相对稳定,93%的参与者保持在“基本满足需求”,78%的参与者保持在“基本未满足需求”。与非西班牙裔白人参与者相比,非西班牙裔黑人参与者在任何时间点都有较低的“基本满足需求”班级成员的几率(OR, 0.60;[95% CI, 0.42-0.84]),从2010年到2014年,进入一般满足需求类别的几率较低,进入未满足金融需求类别的几率较高(OR, 0.33;[95% ci, 0.13-0.86];OR = 3.02;[95% CI, 1.16-7.87])。结论:基于未满足需求的潜在应激等级与高血压和糖尿病状态相关。随着时间的推移,在潜在的阶级成员和阶级之间的转变上观察到种族和民族的差异。与未满足需求、高血压和糖尿病相关的潜在压力等级以及在等级之间转换的能力可能解释了心血管健康中种族和民族差异的持续存在。针对未满足需求的干预措施可用于应对这些差异。
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