Mukta Kumar , Masayo Watanabe , Vivekanand Singh , Linda D. Cooley
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引用次数: 2
Abstract
Clinical presentation of acute myelogenous leukemia (AML) in infants as an ovarian tumor is extremely rare, although AML is well reported in older children and adults. Granulocytic sarcoma or chloroma is an extramedullary tumor seen in AML and myeloid and myeloproliferative disorders. We report a case of a 5-month-old female infant who presented with bilateral ovarian masses. Based on a left oophorectomy and bone marrow evaluation, the patient was diagnosed with bilateral ovarian granulocytic sarcoma and erythroleukemia (French-American-British type M6 AML). Our patient has unusual cytogenetics involving rearrangements of chromosomes 1, 11, and 16. The patient has received chemotherapy and is alive at 2 years from the diagnosis.
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