Clustering of hyperlipidemia, hyperglycemia, alcohol drinking, overweight and central obesity and hypertension in Mongolian people, China

Mingzhi Zhang , Buren Batu , Weijun Tong , Yongyue Liu , Yanbin Liu , Yonghong Zhang
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引用次数: 4

Abstract

Background and objectives

There is little knowledge on whether clustering of hyperlipidemia, hyperglycemia, alcohol drinking, overweight and central obesity increases risk of hypertension in Mongolian people of rural and animal husbandry area.

Methods

A cross sectional study was performed in a Mongolian population. Demographic data, lifestyle factors, family history of hypertension, blood pressure measurements, physical examination were obtained and blood glucose and lipids were examined in 2532 individuals.

Results

Hyperlipidemia, hyperglycemia, alcohol drinking, overweight and central obesity were all independently associated with hypertension (all P < 0.01), and clustering of these risk factors correlated with risk of hypertension in Mongolian people. Age and gender-adjusted OR of hypertension for clustering of two, three and four or more factors were 1.878(1.262, 2.795), 3.735(2.529, 5.516) and 4.361(2.886, 6.589), respectively.

Conclusions

Hyperlipidemia, hyperglycemia, alcohol drinking, overweight and central obesity were independent risk factors of hypertension. Risk of hypertension in Mongolian people increased with the number of up to five risk factors in clusters. It is imperative that risk factors be controlled at the same time for the primary prevention and early treatment of hypertension.

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中国蒙古族高脂血症、高血糖症、饮酒、超重、中心性肥胖和高血压的聚集性研究
背景与目的高脂血症、高血糖症、饮酒、超重和中心性肥胖是否会增加农牧区蒙古族人群高血压的发病风险,目前尚不清楚。方法对蒙古族人群进行横断面研究。获得2532例患者的人口统计资料、生活方式因素、高血压家族史、血压测量、体格检查和血糖、血脂检查。结果高脂血症、高血糖症、饮酒、超重和中心性肥胖均与高血压独立相关(均P <0.01),这些危险因素的聚类与蒙古族高血压风险相关。2、3、4个及以上因素聚类的高血压年龄、性别调整OR分别为1.878(1.262、2.795)、3.735(2.529、5.516)、4.361(2.886、6.589)。结论高血糖、低血糖、饮酒、超重和中心性肥胖是高血压的独立危险因素。蒙古人的高血压风险随着聚集性危险因素达到5个而增加。在控制危险因素的同时进行高血压的一级预防和早期治疗是十分必要的。
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