Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents (OECD TG 409)

Abstract

922. This assay determines the general toxicity of chemicals in non-rodents after 90 days of oral dosing (by gavage, via the diet, in drinking water or in capsules). The most commonly used non-rodent species is the dog, which should be of a defined breed (beagle usually). It provides information on major toxic effects and target organ toxicity likely to arise from the post-weaning period until well into adulthood. OECD TG 409 was adopted in September 1981 and revised in September 1998.