Clinical and epidemiological characteristics and factors associated with mortality in adult patients admitted by COVID -19 in intensive care

O. A. Barbosa, Talita Guimarães Andrade, Maria Danielly de Almeida Sousa, Sofia Esmeraldo Rodrigues, Paulo Robson Viana, M. Moretto, M. Teles, H. L. Rocha
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Abstract

Objectives : We conducted a retrospective, observational, case-control type study to define the clinical and epidemiological characteristics and factors associated with death in the intensive care of these patients. Methodology : We reviewed the medical records and examinations of 72 patients with confirmed diagnosis of SARS-CoV-2 infection in our intensive care unit (ICU). Results : In the review, 20 patients died during hospitalization, and 52 were discharged from the ICU. Associated with mortality, we verified, after analysis, that age, male gender, smoking, tropononin levels, creatinine, lymphocytes, bilirubin, and respiratory compliance were statistically significant. SOFA, APACHE 2, and SAPS 2 scores were good predictors of ICU mortality in this population. Conclusion : Despite several limitations, our study was able to demonstrate a series of clinical and laboratory factors associated with ICU death by COVID-19, compatible with international and multicenter case series
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重症监护成年COVID -19患者的临床和流行病学特征及死亡相关因素
目的:我们进行了一项回顾性、观察性、病例对照型研究,以确定重症监护患者的临床和流行病学特征以及与死亡相关的因素。方法:回顾性分析我院重症监护病房(ICU)确诊为SARS-CoV-2感染的72例患者的病历和检查结果。结果:本组患者住院期间死亡20例,出院52例。与死亡率相关,我们在分析后证实,年龄、男性、吸烟、肌钙蛋白水平、肌酐、淋巴细胞、胆红素和呼吸顺应性具有统计学意义。SOFA、APACHE 2和SAPS 2评分是该人群ICU死亡率的良好预测指标。结论:尽管存在一些局限性,但我们的研究能够证明一系列与COVID-19 ICU死亡相关的临床和实验室因素,与国际和多中心病例系列相一致
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