Treatment of pain in patients with mine blast wounds during treatment in military medical clinical centers

I. Kuchyn, V. Horoshko
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Abstract

Considering the war situation in Ukraine, the treatment of pain in patients with mine blast injuries is of great importance in today's medical practice because, during the Anti-Terrorist Operation/Joint Forces Operation, such injuries account for more than 25%, and chronic pain after such injuries is diagnosed in 83.3% of cases. Such injuries are characterized by significant damage. Data on pain treatment at the stage of treatment in military medical clinical centers are scarce.The goal of the work. To investigate the results of pain treatment of patients with mine blast wounds at the stage of treatment in military medical clinical centers of the Armed Forces of Ukraine.Methods. Data on the treatment of 280 patients with mine blast injuries are presented. Pain intensity was diagnosed using a visual analog scale. The Shapiro-Wilk test was used to check the distribution of quantitative indicators for normality. The distribution law differed from the normal one; the median value (Me) and the interquartile range (QI-QIII) were given to represent quantitative indicators. The comparison of indicators in two groups was carried out according to the Mann-Whitney test. To analyze the dynamics of the indicators, the Friedman test for related samples was used, the posterior comparison was carried out using the Bonferroni correction. For qualitative indicators, the absolute frequency of symptom manifestation and the relative frequency (%) are presented, and for the comparison of two groups, the chi-square test was used, taking into account the correction for continuity. When conducting the analysis in all cases, the critical significance level was equal to 0.05.Results. Pain intensity according to VAS before analgesia at the stage of treatment in military medical clinical centers shows that before analgesia in group 2 it was significantly higher than in patients of group 1 (p<0.001) and is 7 points – severe pain. Patients of group 1 experienced pain of average intensity on admission - 4 points. After analgesia, the average value of the VAS indicator in the two groups was practically not different, but it was statistically significant (p=0.012), this indicator was higher in group 2. During in-patient observation for 2-6 days (p<0.001) and before discharge from in-patient treatment (p=0.013) values of the VAS indicator in group 2 were higher than in group 1. The dynamics of the intervals between analgesia indicate that in groups 1 and 2 there is a statistically significant difference during the 1 day of observation (p=0.005) and 9-14 days of observation (p<0.001).Conclusions. Taking into account the obtained data, it is clear that the effectiveness of analgesia, both in the previous stages of treatment and during the transportation of patients, was at a low level. It is also worth noting that during discharge from inpatient treatment, patients still felt mild pain. Patients with mine blast injuries have a high risk of chronic pain. The obtained results of the study indicate ways to improve the results of treatment in this category of patients. Achieving good pain control in the early stages of treatment and maintaining continuity of care during evacuation can potentially reduce the frequency of chronic pain.
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在军事医疗临床中心治疗期间地雷炸伤患者疼痛的治疗
考虑到乌克兰的战争局势,治疗地雷炸伤患者的疼痛在今天的医疗实践中非常重要,因为在反恐行动/联合部队行动中,此类伤害占25%以上,并且在此类伤害后诊断出慢性疼痛的病例占83.3%。这种伤害的特点是严重的损伤。在军事医疗临床中心治疗阶段的疼痛治疗数据很少。工作的目标。目的了解乌克兰武装部队军事医疗临床中心治疗阶段地雷爆炸伤患者的疼痛治疗效果。本文介绍了280例地雷炸伤患者的治疗情况。采用视觉模拟量表诊断疼痛强度。采用Shapiro-Wilk检验检验定量指标分布是否符合正态性。分布规律与正常分布规律不同;用中位数(Me)和四分位数间距(qi - qi)表示定量指标。两组指标比较采用Mann-Whitney检验。为了分析指标的动态,对相关样本采用Friedman检验,后验比较采用Bonferroni校正。定性指标给出症状表现的绝对频率和相对频率(%),两组比较采用卡方检验,考虑连续性校正。对所有病例进行分析时,临界显著性水平为0.05。根据军队医疗临床中心治疗阶段镇痛前VAS疼痛强度显示,2组患者镇痛前疼痛强度明显高于1组患者(p<0.001),为7分-剧烈疼痛。1组患者入院时疼痛平均强度- 4分。镇痛后,两组患者VAS指标的平均值几乎没有差异,但差异有统计学意义(p=0.012), 2组患者VAS指标更高。在住院观察2 ~ 6 d期间(p<0.001)和出院前(p=0.013),组2的VAS指标均高于组1。镇痛间隔动态显示,1、2组在观察1天(p=0.005)和观察9 ~ 14天(p<0.001)差异有统计学意义。考虑到获得的数据,很明显,镇痛的有效性,无论是在治疗的前阶段还是在患者的运输过程中,都处于较低的水平。同样值得注意的是,在住院治疗出院时,患者仍然感到轻微的疼痛。地雷炸伤的病人患慢性疼痛的风险很高。所获得的研究结果为改善这类患者的治疗结果指明了途径。在治疗的早期阶段实现良好的疼痛控制,并在撤离期间保持护理的连续性,可以潜在地减少慢性疼痛的发生频率。
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