{"title":"The Role of the Nucleotide-Excision Repair (NER) Pathway in Soft Tissue Sarcomas: A Review and a Focus on Its Potential as a Therapeutic Target","authors":"Pillozzi Serena, Scolari Federico, Pasqui Adriano, Boddi Anna, Fancelli Sara, Caliman Enrico, Palchetti Ilaria, Bernini Andrea, Petroni Giulia, Scoccianti Guido, Campanacci Domenico, Antonuzzo Lorenzo","doi":"10.31038/cst.2023824","DOIUrl":null,"url":null,"abstract":"Soft tissue sarcomas (STS) are low-incidence, mesenchymal-derived tumors represented by more than 50 his to types. Despite the latest developments, the rates of patients developing recurrent and metastatic disease are high. Many of the mechanisms underlying STS are still unknown","PeriodicalId":72517,"journal":{"name":"Cancer studies and therapeutics","volume":"458 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer studies and therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31038/cst.2023824","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Soft tissue sarcomas (STS) are low-incidence, mesenchymal-derived tumors represented by more than 50 his to types. Despite the latest developments, the rates of patients developing recurrent and metastatic disease are high. Many of the mechanisms underlying STS are still unknown