Feasibility and Outcome of Laparoscopic Approach for Acute Generalized Peritonitis in Africa: Single Low-Center Results After 25 Consecutive Cases in Cameroon

Bang Guy Aristide, Nana Oumarou Blondel, S. E. Patrick, B. Georges, Essomba Arthur Georges
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Abstract

surgery is associated with lower morbidity and mortality. However, the laparoscopic approach to the management of peritonitis remains marginalized in low and middle-income countries (LMICs) due to financial and technical limitations.Methods: We conducted a seven-year prospective study on patients with acute generalized peritonitis in Yaounde, Cameroon. Inclusion criteria were an age range of between 5 to 55 years, admission within 48 hours after the onset of symptoms, hemodynamic stability, and no major comorbidities. Excluded from this study were patients with colonic perforation, prior history of abdominal surgery, or primary and localized peritonitis after proper resuscitation. The patients included were managed via laparoscopy; operative and postoperative data were collected and analyzed. Some technical artifices were used to circumvent the lack of standardequipment. Results: The study involved twenty-five patients with a mean age of 32.1 years. The etiology of peritonitis was identified as appendicitis in 20 cases, perforated duodenal ulcer in 2 cases, gastric ulcer perforation in 2 cases, and jejunal perforation in 1 case. In two cases (8%), the operation was onverted to laparotomy. The postoperative course was uneventful in 21 cases (84%), whereas morbidity was seen in 4 cases (16%); no mortality was recorded. The mean length of hospital stay was 5.5 days.Conclusions: This study demonstrates that the laparoscopic management of acute generalized peritonitis in African LMICs is afeasible, safe, and effective surgical option in properly selected patients.
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腹腔镜入路治疗非洲急性广泛性腹膜炎的可行性和结果:喀麦隆25例连续病例后的单一低中心结果
手术与较低的发病率和死亡率相关。然而,由于财政和技术限制,腹腔镜治疗腹膜炎的方法在低收入和中等收入国家(LMICs)仍然被边缘化。方法:我们对喀麦隆雅温得的急性全身性腹膜炎患者进行了一项为期7年的前瞻性研究。纳入标准为年龄范围在5至55岁之间,出现症状后48小时内入院,血流动力学稳定,无主要合并症。本研究排除了结肠穿孔、既往腹部手术史或经适当复苏后的原发性和局限性腹膜炎患者。纳入的患者通过腹腔镜进行治疗;收集并分析手术及术后资料。一些技术手段被用来规避缺乏标准设备的问题。结果:研究纳入25例患者,平均年龄32.1岁。腹膜炎病因为阑尾炎20例,十二指肠溃疡穿孔2例,胃溃疡穿孔2例,空肠穿孔1例。2例(8%)手术转为剖腹手术。术后21例(84%)顺利,4例(16%)出现并发症;无死亡记录。平均住院时间为5.5天。结论:本研究表明,腹腔镜治疗急性广泛性腹膜炎在非洲低收入国家是可行的,安全和有效的手术选择适当选择的患者。
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