Mucormycosis, COVID-19 and Acute Lymphoid Leukemia: Case Report

E. L. Cordero-Hernández, C. Martínez-Murillo, Gilberto Barranco-Lampón, Itsel Arias-Castro, A. Santoyo-Sánchez, C. Ramos-Peñafiel
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引用次数: 1

Abstract

Introduction: During the era of COVID-19, an increase has surged in the number of cases of mucormycosis; the use of high doses of steroids, and states of immunosuppression such as diabetes are the main related risk factors. In the treatment of acute leukemia, it is recommended to reduce the dose of chemotherapy, postponing highly myeloablative schemes and the use of caution with monoclonal antibodies. Case presentation: We present the case of a patient (25 years-old male) with acute lymphoblastic leukemia and COVID-19 confirmed infection who developed rhino-cerebral mucormycosis during the induction stage. Conclusion: In the age of COVID-19, taking samples through a nasal swab should be avoided in individuals with risk of infection from mucormycosis, such as diabetes, cancer, or individuals treated with high doses of steroids.
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毛霉病、COVID-19和急性淋巴性白血病1例报告
导言:在2019冠状病毒病(COVID-19)时代,毛霉病病例数量激增;使用高剂量类固醇和免疫抑制状态(如糖尿病)是主要的相关危险因素。在治疗急性白血病时,建议减少化疗剂量,推迟高度清髓方案,谨慎使用单克隆抗体。病例介绍:我们报告一例患有急性淋巴细胞白血病和COVID-19确诊感染的患者(25岁男性),他在诱导期出现了鼻-脑毛霉菌病。结论:在COVID-19时代,应避免对有毛霉菌感染风险的个体(如糖尿病、癌症)或接受高剂量类固醇治疗的个体通过鼻拭子取样。
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