MannKind Finally Finds a Partner for its Inhaled Insulin Afrezza® in Sanofi

Heather Cartwright
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Abstract

Sanofi has licensed global rights to MannKind’s rapid-acting inhaled insulin Afrezza® (insulin human), which was approved by the US FDA in June 2014 for the treatment of diabetes mellitus at the third attempt. The drug will diversify Sanofi’s diabetes portfolio ahead of the 2015 patent expiry of its long-acting basal insulin analogue Lantus® (insulin glargine), which leads the diabetes market with sales of more than US$7 B in 2013. Considerable uncertainty surrounds the commercial potential of Afrezza, however.
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MannKind终于在赛诺菲找到了吸入胰岛素Afrezza®的合作伙伴
赛诺菲已获得MannKind速效吸入胰岛素Afrezza®(人胰岛素)的全球授权,该产品于2014年6月获得美国FDA第三次批准,用于治疗糖尿病。在长效基础胰岛素类似物Lantus®(甘精胰岛素)2015年专利到期之前,该药将使赛诺菲的糖尿病产品组合多样化。Lantus®在2013年以超过70亿美元的销售额引领糖尿病市场。然而,围绕Afrezza的商业潜力存在相当大的不确定性。
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