Pharmaceutical Evaluation for 10% Phenytoin Powders

Y. Kagawa, K. Sasaki, M. Matsushima, S. Inagaki, Michio Kojima
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Abstract

A dispensing test of 10% phenytoin powders (10% DPH), which has the same bioavailability as the tablet, was investigated. Pharmaceutical characteristics including an apparent density, a dispersibility, grouping properties and an angle of repose of 10% DPH passed the criteria for dispensing from the hospital pharmacy. Next, according to clinical formulas, we designed the eight standard formulas that consisting 10% DPH with 10% phenobarbital powders, zonisamide powders, carbamazepine
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10%苯妥英粉末的药学评价
研究了与片剂具有相同生物利用度的10%苯妥英粉剂(10% DPH)的配药试验。药物特性包括表观密度、分散性、分组特性和10% DPH的休止角通过了医院药房的调剂标准。其次,根据临床处方,设计了10% DPH与10%苯巴比妥粉剂、唑尼沙胺粉剂、卡马西平组成的8个标准配方
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