{"title":"Clinical Significance of Cytogenetics in Myelodysplastic Syndromes","authors":"A. Haddad, J. Maciejewski, M. Kalaycio","doi":"10.1309/EWKEBC48R8KYETR3","DOIUrl":null,"url":null,"abstract":"The myelodysplastic syndromes (MDSs) are a heterogeneous group of diseases characterized by hemopoietic insufficiency associated with cytopenias due to dysfunctional hematopoietic stem cells. Myelodysplastic syndromes sometimes progress to acute myelogenous leukemia. The cytopenias caused by MDS lead to serious complications such as bleeding, infections, and symptomatic anemia. Cytogenetic abnormalities in MDS patients have an important role in categorizing these syndromes and are important in predicting prognosis and treatment response.","PeriodicalId":54328,"journal":{"name":"Labmedicine","volume":"87 1","pages":"367-370"},"PeriodicalIF":1.0000,"publicationDate":"2015-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Labmedicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1309/EWKEBC48R8KYETR3","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
引用次数: 1
Abstract
The myelodysplastic syndromes (MDSs) are a heterogeneous group of diseases characterized by hemopoietic insufficiency associated with cytopenias due to dysfunctional hematopoietic stem cells. Myelodysplastic syndromes sometimes progress to acute myelogenous leukemia. The cytopenias caused by MDS lead to serious complications such as bleeding, infections, and symptomatic anemia. Cytogenetic abnormalities in MDS patients have an important role in categorizing these syndromes and are important in predicting prognosis and treatment response.
期刊介绍：
Lab Medicine is a peer-reviewed biomedical journal published quarterly by the ASCP and Oxford University Press. The journal invites submission of manuscripts on topics related to clinical chemistry and microbiology, hematology, immunology, transfusion medicine, molecular diagnostics, cytology, histology, and laboratory administration and management. Original research, reviews, and case reports are considered for publication. Lab Medicine is indexed (under the title Laboratory Medicine) by the National Library of Medicine and is included in the PubMed database.
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