Investigation of the Appropriate Use of Antiseptics with Cotton Swabs.

Y. Yoshida, Y. Enomoto, Yuki Hasumi, M. Makimura
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Abstract

To determine their most appropriate use for medical purposes, we investigated the method for preparing antiseptic-containing cotton swabs. We measured the amount of antiseptic solution contained in a cotton swab according to the water-absorbency method for absorbent cotton as described in detail in the Japanese Pharmacopoeia.We tested three antiseptic agents which are frequently used in hospitals: povidone-iodine, benzalkonium chloride and chlorhexidine gluconate. Since the weight of cotton swabs from various manufacturers differed significantly, the amount of water or antiseptic solution contained in each swab was also different.Based on the results of these measurements, we additionally evaluated the amount in each solution-containing cotton swab prepared in a medical setting. Judging from the volume of nonabsorbed antiseptic solution, we found that the actual amount used was slightly less than 90% of the calculated amount.It therefore seems that the excessive use of antiseptic agents might be avoided, and health expenditures thus can be reduced, if we could make a manual for preparing antiseptic-containing cotton swabs based on the present results, and thereafter prepare them according to the instructions of the manual at hospitals.
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用棉签适当使用消毒剂的调查。
为了确定其最适合的医疗用途,我们研究了制备含防腐剂棉签的方法。我们根据日本药典中详细描述的吸水棉的吸水法测量棉签中含有的抗菌溶液的量。我们测试了医院常用的三种防腐剂:聚维酮碘、苯扎氯铵和葡萄糖酸氯己定。由于不同厂家棉签的重量差别很大,所以每个棉签所含的水或消毒溶液的量也不同。根据这些测量结果,我们进一步评估了在医疗环境中制备的每个含棉拭子溶液中的含量。从未吸收的防腐液的体积来看,我们发现实际使用量略小于计算量的90%。因此,如果我们能在目前的结果基础上制定一份含防腐剂棉签的制备手册,然后在医院按照手册的指示制备棉签,似乎可以避免过度使用防腐剂,从而减少卫生支出。
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