Inflammation and autoimmunity in atherosclerosis

IF 1.4 Q3 RHEUMATOLOGY Reumatologia Pub Date : 2022-02-28 DOI:10.5114/reum.2022.113364
S. Surma, K. Filipiak
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引用次数: 4

Abstract

Atherosclerosis is a process whose onset can be observed even in the foetal period. A number of risk factors, such as hyperlipidaemia, hyperhomocysteinaemia, arterial hypertension, hyperuricaemia, smoking, metabolic syndrome, hypertriglyceridaemia, and diabetes, accelerate the progression of atherosclerotic lesions leading to the development of atherosclerotic cardiovascular disease (ASCVD) [1]. Atherosclerotic cardiovascular disease is defined as coronary artery disease (CAD), cerebrovascular disease, or peripheral arterial disease of atherosclerotic origin. This disease represents the number one cause of morbidity and mortality worldwide. The number of patients with cardiovascular diseases in the world in 2019 was 523 million, while the number of deaths due to them reached 18.6 million [2].
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动脉粥样硬化中的炎症和自身免疫
动脉粥样硬化是一个甚至在胎儿期就可以观察到的发病过程。许多危险因素,如高脂血症、高同型半胱氨酸血症、动脉高血压、高尿酸血症、吸烟、代谢综合征、高甘油三酯血症和糖尿病,加速了动脉粥样硬化病变的进展,导致动脉粥样硬化性心血管疾病(ASCVD)的发展。动脉粥样硬化性心血管疾病被定义为冠状动脉疾病(CAD)、脑血管疾病或动脉粥样硬化起源的外周动脉疾病。这种疾病是全世界发病率和死亡率的头号原因。2019年,全球心血管疾病患者人数为5.23亿人,而心血管疾病导致的死亡人数达到1860万人。
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来源期刊
Reumatologia
Reumatologia Medicine-Rheumatology
CiteScore
2.70
自引率
0.00%
发文量
44
审稿时长
10 weeks
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