Phytochemical screening and antimicrobial activity of Erigeron karvinskianus DC

Neithongunuo Angela Belho, Peter Solo, Gaijuliu Therese, Senchumbeni Yanthan, KP Sophia, Chongliu K
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引用次数: 1

Abstract

Erigeron karvinskianus , a small herb, belonging to the family Asteraceae, was identified by the Botanical Survey of India, Shillong, Meghalaya. The plant parts such as stem, roots and leaves were dried, powdered and subjected to Soxhlet extraction with various solvents based on its polarity. Phytochemical screening of the methanolic and aqueous extract detected the presence of alkaloids, flavonoids, phenolic compounds and tannins. The extracts were subject to antimicrobial assay (DPPH) against four micro-organisms, viz ., E . Coli, S. Sureus, A. Niger and C. Albicans. The methanolic extracts of leaves exhibited significant antibacterial activity with zones of inhibition of 19.5mm (500 µg/µl) against E. coli (Gentamicin as positive control, 18.5 mm). The aqueous extract of the stem-roots showed effective antifungal activity with zones of inhibition measuring 10.5mm (500 µg/µl) against A. niger (Amphotericin B as positive control, 10.0 mm). The study proposes that E. karvinskianus can be considered as a potent plant-based antimicrobial agent.
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金盏花植物化学筛选及抑菌活性研究
Erigeron karvinskianus是菊科的一种小型草本植物,由印度梅加拉亚邦西隆植物调查所鉴定。将植物的茎、根、叶等部分干燥、制成粉末,并根据极性用不同的溶剂进行索氏提取。植物化学筛选甲醇和水提物检测到生物碱、黄酮类化合物、酚类化合物和单宁。提取液对四种微生物进行抑菌试验(DPPH),即E。大肠杆菌,葡萄球菌,尼日尔杆菌和白色念珠菌。叶片甲醇提取物对大肠杆菌的抑菌活性显著,抑菌带为19.5mm(500µg/µl)(阳性对照庆大霉素为18.5 mm)。茎根水提物对黑曲霉(Amphotericin B为阳性对照,10.0 mm)的抑制区为10.5mm(500µg/µl)。该研究表明,卡尔文氏杆菌可以被认为是一种有效的植物抗菌剂。
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