Ultrasound-assisted a domino three-component reaction to polycyclic selenopyrans synthesis

Hadi Sedighian, Kaveh Imani, A. Bazgir
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Abstract

Abstract A novel and efficient three-component reaction of substituted benzoyl chlorides, potassium selenocyanate and vinyl malononitriles was developed for the synthesis of polycyclic selenopyrans via an ultrasound-assisted domino vinylogous nucleophilic reaction/intramolecular selenocyclization/imine-enamine tautomerization reaction. Introducing a simple one-step method and use of available starting materials and mild reaction conditions are the most important advantages of this strategy. Graphical Abstract
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超声辅助合成多环硒吡喃的多米诺三组分反应
摘要以取代苯甲酰氯、硒氰酸钾和乙烯基丙二腈为原料,通过超声辅助的多米诺骨牌亲核反应/分子内硒环化反应/亚胺-烯胺互变异构反应合成了多环硒吡喃。引入简单的一步法,使用可用的起始材料和温和的反应条件是该策略最重要的优点。图形抽象
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