{"title":"[Nutritional therapy of gout].","authors":"Beate Nickolai, C. Kiss","doi":"10.1024/0040-5930/a000772","DOIUrl":null,"url":null,"abstract":"Nutrition and nutritional behaviours have been found to play a major role in the development of gout. Studies show that body mass index (BMI), as well as excessive intake of alcoholic beverages, meat, soft drinks and fruit juices increase the risk of developing gout. Similarly, dairy products and coffee have been seen to decrease the risk of hyperuricemia and gout, as they increase the excretion of uric acid. Flares of gout are often caused by large meals and high alcohol consumption. Each additional intake of meat portion per day increases the risk of gout by 21 %. Taking total alcohol consumption into account, the risk of gout increases after one to two standard drinks. In contrast to previous assumptions purine-rich plant foods like legumes and vegetables do not increase the risk of gout. The current dietary guidelines take into account nutritional factors, which not only consider purine intake, but also their endogenous production and their influence on renal excretion. A balanced diet based on the Swiss healthy eating guideline pyramid as well as the Mediterranean diet is appropriate for this patient population. The treatment of gout is multi-faceted, since this patient population presents other comorbidities such as obesity, diabetes mellitus, dyslipidemia and hypertension. Collectively, these risk factors are diet dependent and require a treatment strategy that is centered on modifying one's nutrition and nutritional behaviours. The aim of such therapy is to educate the patient as well as treat the accompanying comorbidities with the goal of decreasing serum uric acid values. Motivated patients require consultation and follow-up care in order to be able to actively decrease the serum uric acid.","PeriodicalId":87030,"journal":{"name":"Therapeutische Umschau und medizinische Bibliographie. Revue therapeutique et bibliographie medicale","volume":"56 1","pages":"153-8"},"PeriodicalIF":0.0000,"publicationDate":"2016-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Therapeutische Umschau und medizinische Bibliographie. Revue therapeutique et bibliographie medicale","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1024/0040-5930/a000772","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6

Abstract

Nutrition and nutritional behaviours have been found to play a major role in the development of gout. Studies show that body mass index (BMI), as well as excessive intake of alcoholic beverages, meat, soft drinks and fruit juices increase the risk of developing gout. Similarly, dairy products and coffee have been seen to decrease the risk of hyperuricemia and gout, as they increase the excretion of uric acid. Flares of gout are often caused by large meals and high alcohol consumption. Each additional intake of meat portion per day increases the risk of gout by 21 %. Taking total alcohol consumption into account, the risk of gout increases after one to two standard drinks. In contrast to previous assumptions purine-rich plant foods like legumes and vegetables do not increase the risk of gout. The current dietary guidelines take into account nutritional factors, which not only consider purine intake, but also their endogenous production and their influence on renal excretion. A balanced diet based on the Swiss healthy eating guideline pyramid as well as the Mediterranean diet is appropriate for this patient population. The treatment of gout is multi-faceted, since this patient population presents other comorbidities such as obesity, diabetes mellitus, dyslipidemia and hypertension. Collectively, these risk factors are diet dependent and require a treatment strategy that is centered on modifying one's nutrition and nutritional behaviours. The aim of such therapy is to educate the patient as well as treat the accompanying comorbidities with the goal of decreasing serum uric acid values. Motivated patients require consultation and follow-up care in order to be able to actively decrease the serum uric acid.
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【痛风的营养疗法】。
营养和营养行为已被发现在痛风的发展中起着重要作用。研究表明,身体质量指数(BMI)以及过量摄入酒精饮料、肉类、软饮料和果汁会增加患痛风的风险。同样,奶制品和咖啡也被认为可以降低高尿酸血症和痛风的风险,因为它们增加了尿酸的排泄。痛风的发作通常是由暴饮暴食和大量饮酒引起的。每天多吃一份肉,患痛风的风险就会增加21%。考虑到总酒精消费量,痛风的风险在一到两杯标准饮料后增加。与之前的假设相反,富含嘌呤的植物性食物,如豆类和蔬菜,不会增加痛风的风险。目前的膳食指南考虑了营养因素,不仅考虑了嘌呤的摄入,还考虑了嘌呤的内源性产生及其对肾排泄的影响。基于瑞士健康饮食指南金字塔以及地中海饮食的均衡饮食适合该患者人群。痛风的治疗是多方面的,因为这一患者群体存在其他合并症,如肥胖、糖尿病、血脂异常和高血压。总的来说,这些风险因素依赖于饮食,需要一种以改变个人营养和营养行为为中心的治疗策略。这种治疗的目的是教育患者以及治疗伴随的合并症,目的是降低血清尿酸值。有动机的患者需要咨询和随访护理,以便能够积极降低血清尿酸。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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