Primary Appendiceal Gastrointestinal Stromal Tumor

IF 0.1 Q4 PATHOLOGY AJSP: reviews & reports Pub Date : 2021-12-21 DOI:10.1097/PCR.0000000000000410
Joseph S. Kim, A. Jhala, Kristen M. Stashek, R. Tondon
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Abstract

Abstract Primary appendiceal gastrointestinal stromal tumor is extremely rare. To our knowledge, only 17 cases have been reported so far. Presented is a case of an 84-year-old woman who underwent elective laparoscopic right partial colectomy for an ileocecal mass found during colonoscopy. On gross examination, a 0.8-cm well-defined tan-white nodule was present in the distal portion of the appendix. Histology of the nodule showed proliferation of irregular fascicles of bland spindle cells, which stained positive for DOG1 (Ano1) and CD117 (KIT) and negative for S-100 and SMA. We report the incidental primary gastrointestinal stromal tumor of the appendix and discuss its biological behavior.
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原发性阑尾胃肠道间质瘤
摘要原发性阑尾胃肠道间质瘤极为罕见。据我们所知,到目前为止只报告了17例。本文报告一位84岁妇女,因结肠镜检查发现回盲肿块,接受选择性腹腔镜右结肠部分切除术。大体检查,在阑尾远端可见一0.8 cm清晰的棕白色结节。结节的组织学表现为不规则的淡梭形细胞束的增生,DOG1 (Ano1)和CD117 (KIT)染色呈阳性,S-100和SMA呈阴性。我们报告偶发的原发性胃肠道间质肿瘤的阑尾和讨论其生物学行为。
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