Impaired gastric mucosal integrity identified by confocal endomicroscopy in Helicobacter pylori‐negative functional dyspepsia

Abstract

Low‐grade inflammation may be involved in the pathogenesis of functional dyspepsia (FD). We hypothesis that altered gastric permeability is involved in the onset and persistence of this disorder. Therefore, our aim was to evaluate gastric mucosal integrity and mast cell numbers in patients with FD.