Pachydermoperiostosis with Chronic Diarrhoea: A Case Report

M. A. H. Khan, Md Nahiduzzamane Shazzad, Shamim Ahmed, S. Haq
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Abstract

Pachydermoperiostosis (PDP) is a rare autosomal disorder characterized by periostosis, clubbing, thickening of the skin (pachyderma) of the face and scalp, seborrhea and hyperhydrosis. It is the primary form of hypertrophic osteoarthropathy (HOA), the other name of which is Touraine- Solente-Golé syndrome. PDP has various organ involvements and there are some rare associations of PDP with other disorders. Here we describe a 16-year-old boy who presented with skin and skeletal manifestations typical of PDP who also had chronic diarrhea, abdominal pain and weight loss. After giving treatment with risedronate sodium and mesalazine he got significant improvement in his skeletal and abdominal complaints. Bangladesh Med J. 2021 Sept; 50(3): 52-55
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厚皮包膜病合并慢性腹泻1例
厚皮厚皮病(PDP)是一种罕见的常染色体疾病,其特征是面部和头皮的骨膜病,棒状,皮肤增厚(厚皮病),皮脂漏和多汗症。它是肥厚性骨关节病(HOA)的主要形式,其另一个名称是Touraine- solente - gol综合征。PDP累及多个器官,也有一些罕见的PDP与其他疾病的关联。在这里,我们描述了一个16岁的男孩,他的皮肤和骨骼表现为典型的PDP,同时也有慢性腹泻,腹痛和体重减轻。在给予利塞膦酸钠和美沙拉嗪治疗后,他的骨骼和腹部症状有了明显改善。孟加拉国Med . 2021年9月;50 (3): 52-55
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