Modern clinico-epidemiological features of the course of some communicable infectious zooanthroponous exanthemas in times of war

O. Fedorenko, S. Ivanov, V. Stepanenko
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Abstract

Objective — to study and analyze modern clinical and epidemiological features of emerging zooanthroponoses, legal and organizational measures to ensure the sanitary and epidemiological well­being of the population of Ukraine in wartime conditions and active hostilities on a large area of the south and east of the country. Materials and methods. An analytical review of a number of scientific publications devoted to the study of zoonotic diseases of the population accompanied by the appearance of exanthems on the skin was carried out. State legislative acts on issues of ensuring sanitary and epidemic welfare of citizens of Ukraine during wartime were also considered. The search for information was carried out in the medical databases PubMed, Elsevier, High Wire Press, Google Scholar for the period 2000—2022 according to the terms of the catalog of medical topics, subject headings with keywords: «dermatozoonosis», «exanthema», «epidemio­logy», «morbidity», «outbreak». Meta-analyses and reviews of relevant literature were studied. The work presents the principles of a scientific approach to the optimization of preventive and anti-epidemic measures to combat infectious zoonotic diseases, which should contribute to the maximally rational use of the laws of classical epidemiology in the conditions of war in order to increase the practical effectiveness of the anti-epidemic and dermatological services of the Ministry of Health of Ukraine.Results and discussion. The complex socio-economic situation of martial law and forced mass resettlement created quite favorable conditions for increasing the incidence of infectious zoonotic diseases in population, including their real outbreaks in certain territories near the front. The article describes methodical and diagnostic approaches, specific epidemiological principles and dermatological criteria for building effective measures to combat zoonotic diseases. A professional justification of the role and place of each of them in various infectious diseases is given, taking into account the provisions of general epidemiology and traditional dermatological semiotics. Conclusions. The principles of mandatory complexity and qualified impact on the main link of the epidemic process are of great importance in the fight against various groups of infectious diseases. Their clinically justified and timely administrative use is necessary to achieve the goals of eradication, elimination and control of infectious diseases. In Ukraine, there is a sufficient normative and legal framework for the proper provision of sanitary and epidemic welfare of the population. In order to prevent the spread of existing or potential infectious agents, in particular emerging pathogens, it is necessary to develop and improve the already existing emergency response plan, particularly, the infrastructure of the health care system, to create a multi-level network of diagnostic laboratories and an integrated system of epidemiological surveillance. It is proposed to increase the branching of the network of institutions capable of identifying pathogens of zoonoses, hospitalization of those who are already sick and persons suspected of having the disease in conditions that will ensure their isolation and proper treatment, and to develop specific recommendations for the prevention of the spread of pathogens with various transmission routes. The task of such centers should be the comprehensiveness of epidemiological, diagnostic and preventive measures which must be carried out professionally and promptly. Also, one of the priorities should be the retraining of doctors of various specialties (epidemiologists, general practitioners — family doctors, dermatologists) on topical issues of zoonoses surveillance.
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战争时期一些传染性动物人源性传染病的现代临床流行病学特征
目的-研究和分析新出现的人畜传染病的现代临床和流行病学特征,法律和组织措施,以确保乌克兰人口在战时条件下和该国南部和东部大片地区的敌对行动中的卫生和流行病学福祉。材料和方法。对一些科学出版物进行了分析性审查,这些出版物专门研究人口人畜共患疾病并伴有皮肤上出现皮疹。还审议了关于在战时确保乌克兰公民卫生和流行病福利问题的国家立法法案。在医学数据库PubMed, Elsevier, High Wire Press, Google Scholar中搜索2000-2022年期间的信息,根据医学主题目录的条款,主题标题的关键词是:“皮肤病”,“exanthema”,“流行病学”,“发病率”,“爆发”。对相关文献进行meta分析和综述。该工作介绍了以科学方法优化预防和抗流行病措施的原则,以防治传染性人畜共患疾病,这应有助于在战争条件下最大限度地合理利用经典流行病学规律,以提高乌克兰卫生部抗流行病和皮肤科服务的实际效力。结果和讨论。戒严令和被迫大规模重新安置所造成的复杂社会经济状况,为增加人口中传染性动物传染病的发病率创造了相当有利的条件,包括在靠近前线的某些地区实际爆发的疾病。本文描述了方法和诊断方法,具体的流行病学原则和皮肤病标准,以建立有效的措施,以对抗人畜共患疾病。考虑到一般流行病学和传统皮肤符号学的规定,给出了每种药物在各种传染病中的作用和地位的专业理由。强制性复杂性原则和对流行过程主要环节的限定影响原则在防治各类传染病方面具有重要意义。它们的临床合理和及时的行政使用对于实现根除、消除和控制传染病的目标是必要的。在乌克兰,有足够的规范和法律框架为人民提供适当的卫生和流行病福利。为了防止现有的或潜在的传染物,特别是新出现的病原体的传播,有必要制定和改进现有的应急计划,特别是保健系统的基础设施,建立一个多层次的诊断实验室网络和流行病学监测的综合系统。建议增加能够确定人畜共患病病原体的机构网络的分支,使已经患病的人和疑似患病的人住院,使其在确保隔离和适当治疗的条件下住院,并就预防病原体通过各种传播途径传播提出具体建议。这些中心的任务应该是全面的流行病、诊断和预防措施,必须以专业和迅速的方式执行。此外,优先事项之一应该是对不同专业的医生(流行病学家、全科医生——家庭医生、皮肤科医生)进行关于人畜共患病监测的专题培训。
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Prospects for the use of Lipster Mint cream in the complex treatment of herpes zoster Efficacy of treating allergic dermatoses with the original drug of topical mometasone furoate in standard clinical practice Modern etiopathogenetic, clinicopathological and therapeutic aspects of lichen planus The use of narrow-band phototherapy with a wavelength of 311 nm in the treatment of patients with parapsoriasis All-Ukrainian scientific and practical conference with international participation «Scientific and practical dermatovenerology in the conditions of martial law in Ukraine» (November 8 — 9, 2023, Kyiv)
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