Design an efficient method for the synthesis of 2-(1,3-diphenyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazole

Abstract

A simple, highly efficient and environmentally friendly method has been developed for the synthesis of 2-(1,3-diphenyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazole by using  Gadolinium(III) trifluoromethanesulfonate catalyst and ethanol reflux reaction conditions  By using this method. 12 new 2-(1,3-diphenyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazole derivatives were synthesized under optimized reactions conditions. All these new products structures are confirmed by spectral analysis. By this method, we achieved imidazole derivatives with more operational simplicity, short reaction time and good yields (up to 85%).