Evaluation of the efficiency and safety of emergency medical care with uncontrolled arterial hypertension

Abstract

In 91 patients with uncontrolled arterial hypertension, the efficacy and safety of combinations of antihypertensive drugs were compared. 30 patients received a combination of captopril and furosemide; 32 — moxonidine and furosemide; 29 — moxonidine and nifedipine. Drugs were prescribed by fixed randomization using a table of random numbers. It is shown that the combination of captopril and furosemide has a sufficient, but not stable antihypertensive effect, moxonidine and nifedipine, moxonidine and furosemide — a sufficient and stable effect. When using moxonidine and nifedipine, a significantly higher frequency of excessive lowering of blood pressure was detected. The proposed method of registration and evaluation of blood pressure monitoring of funds is easily feasible at the pre-hospital stage.