LONG-TERM CARDIOVASCULAR COMPLICATIONS IN ONCOLOGIC PATIENTS AFTER ANTITUMOR THERAPY (>1 YEAR)

M. L. Kazantseva, E. Oshchepkova, M. Saidova, A. Avalyan, I. Chazova
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Abstract

Oncological and cardiovascular diseases (CVD) hold a leading position among the causes of mortality in many countries of the world, including the Russian Federation [1]. In recent years, a decrease in mortality due to oncologic diseases (OD) is noted around the world thanks to early diagnostics, as well as to the development and implementation of new technologies and therapeutic treatment strategies (chemotherapy, targeted and radiation therapy). Among patients with OD who received chemotherapy and radiation therapy, CVD is one of the leading causes of poor prognosis, including lethal outcomes [2-5]. The long-term cardiotoxic effects of antitumor therapy (chemotherapy, radiation therapy) reduce the survival rate and quality of life of patients who suffer from cancer. Thus, early diagnostics and timely detection of the cardiotoxic effects that follow antitumor treatment is one of the main tasks of cardio-oncology.
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肿瘤患者抗肿瘤治疗后长期心血管并发症(>1年)
肿瘤和心血管疾病(CVD)在包括俄罗斯联邦在内的世界许多国家的死亡原因中占据领先地位[1]。近年来,由于早期诊断以及新技术和治疗策略(化疗、靶向治疗和放射治疗)的开发和实施,世界各地的肿瘤疾病死亡率有所下降。在接受化疗和放疗的OD患者中,CVD是导致预后不良的主要原因之一,包括致死性结局[2-5]。抗肿瘤治疗(化疗、放射治疗)的长期心脏毒性作用降低了癌症患者的生存率和生活质量。因此,早期诊断和及时发现抗肿瘤治疗后的心脏毒性作用是心脏肿瘤学的主要任务之一。
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