Applications of Nanotechnology in the Treatment of Heart Attack and Cancer

K. Sonamuthu
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Abstract

Nanotechnology is unique in that it represents not just one specific area, but a vast variety of disciplines ranging from basic material science to personal care applications. Thus this technology is very advanced and various researches are a heading in this field very quickly One of the important areas of nanotechnology is “nanomedicine,” which, refers to highly specific medical intervention at the molecular scale for diagnosis, prevention and treatment of diseases. The importance of nanotechnology in drug delivery is in the concept and ability to manipulate molecules and super molecular structures for producing devices with programmed functions. Conventional liposomes, polymeric micelles, and nanoparticles are now called “nanovehicles,”. Those conventional drug delivery systems would have evolved to the present state regardless of the current nanotechnology revolution. To achieve efficient drug delivery it is important to understand the interactions of nanomaterials with the biological environment, targeting cell-surface receptors, drug release, and molecular mechanisms of cell signalling involved in pathobiology of the disease under consideration. Several anti-cancer drugs including paclitaxel, doxorubicin, 5-fluorouracil and dexamethasone have been successfully formulated using nanomaterials. The nano drug delivery systems hold great potential to overcome some of the barriers of cells and molecules in heart attack and cancer. Keywords : Nanotechnology, nanomedicine, nanoparticles, liposomes, polymeric micelles, nanoparticles, dendrimers, and nanocrystals. Liposomes and polymer micelles, PLGA, etc,. DOI : 10.7176/APTA/80-03 Publication date :October 31 st 2019
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纳米技术在治疗心脏病和癌症中的应用
纳米技术的独特之处在于它不仅代表了一个特定的领域,而且代表了从基础材料科学到个人护理应用的广泛学科。纳米技术的一个重要领域是“纳米医学”,它指的是在分子尺度上进行高度特异性的医学干预,用于疾病的诊断、预防和治疗。纳米技术在药物传递中的重要性在于其概念和能力,即操纵分子和超分子结构以生产具有编程功能的设备。传统的脂质体、聚合胶束和纳米颗粒现在被称为“纳米载体”。无论当前的纳米技术革命如何,这些传统的药物输送系统都会发展到现在的状态。为了实现有效的药物递送,了解纳米材料与生物环境的相互作用、靶向细胞表面受体、药物释放以及所考虑的疾病病理生物学中涉及的细胞信号传导的分子机制非常重要。包括紫杉醇、阿霉素、5-氟尿嘧啶和地塞米松在内的几种抗癌药物已经成功地使用纳米材料配制。纳米药物输送系统在克服心脏病和癌症中细胞和分子的一些障碍方面具有很大的潜力。关键词:纳米技术,纳米药物,纳米粒子,脂质体,聚合物胶束,纳米粒子,树状大分子,纳米晶体。脂质体、聚合物胶束、聚乳酸等。出版日期:2019年10月31日
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