Protective Effects of Wheat Germ Oil on the IVF, Oxidative Stress and In Vitro Zygote Development in Carbamazepine Treated Epileptic Male Mice

G. E. Manas, G. Najafi
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Abstract

Received: 27 Nov,2019 Accepted: 10 Feb, 2020 Abstract Background and Objectives: Epilepsy is a neurological disorder caused by abnormal electrical discharges from the brain. Carbamazepine is used to treat epilepsy.Over time, this drug may increase oxidative stress and reproductive abnormalities in patients with epilepsy. Wheat germ oil has the highest amount of vitamin E, among other vegetable oils. The aim of this study was to evaluate the effect of wheat germ oil as an antioxidant-rich source on oxidative stress and in vitro fertilization in carbamazepine-treated epileptic male mice.
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小麦胚芽油对卡马西平治疗的癫痫雄性小鼠体外受精、氧化应激和体外合子发育的保护作用
摘要背景与目的:癫痫是一种由大脑异常放电引起的神经系统疾病。卡马西平是用来治疗癫痫的。随着时间的推移,这种药物可能会增加癫痫患者的氧化应激和生殖异常。在其他植物油中,小麦胚芽油的维生素E含量最高。本研究的目的是评价小麦胚芽油作为富含抗氧化剂的来源对卡马西平治疗的癫痫雄性小鼠氧化应激和体外受精的影响。
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