B. Lattuca, F. Leclercq, J. Macia, R. Gervasoni, T. Cung, J. Pasquié, F. Massin, S. Cade, F. Cransac, Mariama Akodad, F. Roubille
{"title":"Colchicine: A Promising Drug in Clinical Translation, A Minireview Focused on Cardiovascular Diseases","authors":"B. Lattuca, F. Leclercq, J. Macia, R. Gervasoni, T. Cung, J. Pasquié, F. Massin, S. Cade, F. Cransac, Mariama Akodad, F. Roubille","doi":"10.17554/j.issn.2309-6861.2015.02.581","DOIUrl":null,"url":null,"abstract":"Colchicine is a venerable drug used for centuries for rheumatic diseases with potential pleiotropic anti-inflammatory effects. One of the main concerns remains the tolerability especially digestive side effects, but this aspect has been improved by many pharmacological improvements. Nowadays, colchine is a promising drug for cancer therapy and cardiovascular diseases with several studies currently going on, an improved therapeutic window and a wider range of translations in cardioprotection but also in atrial fibrillation, ischemic cardiopathy or pericarditis.","PeriodicalId":92802,"journal":{"name":"Journal of clinical cardiology and cardiovascular therapy","volume":"43 1","pages":"311-314"},"PeriodicalIF":0.0000,"publicationDate":"2015-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of clinical cardiology and cardiovascular therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17554/j.issn.2309-6861.2015.02.581","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Colchicine is a venerable drug used for centuries for rheumatic diseases with potential pleiotropic anti-inflammatory effects. One of the main concerns remains the tolerability especially digestive side effects, but this aspect has been improved by many pharmacological improvements. Nowadays, colchine is a promising drug for cancer therapy and cardiovascular diseases with several studies currently going on, an improved therapeutic window and a wider range of translations in cardioprotection but also in atrial fibrillation, ischemic cardiopathy or pericarditis.
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