Clinical observation on the efficacy of intravitreal injection of conbercept in the treatment of macular edema

X. Xiang, Zhengru Huang
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Abstract

Objective To observe the efficacy of intravitreal injection of conbercept in the treatment of macular edema secondary to branch retinal vein occlusion. Methods The data of 33 eyes of 33 patients with macular edema secondary to retinal branch vein occlusion (BRVO-ME) from Jan.2018 to Dec.2018 were retrospectively analysed. The followed-up time was 3 months. Results BCVA(logMAR) were improved at 1, 2, and 3 months after injection, and the difference were statistically significant between before and each time after injection(Z=4.948, 4.642, 4.305, P=0.000, 0.000, 0.000). Central macular retinal thickness (CMT) decreased at 1, 2, and 3 months after injection, and the difference were statistically significant(Z=4.315, 4.404, 4.387, P=0.000, 0.000, 0.000). Conclusion Intravitreal injection of conbercept can improve vision and reduce macular edema in the treatment of retinal branch vein occlusion secondary to macular edema in a short period of time. Key words: Occlusion, vein, retinal; Edema, macular; Conbercept, injection, intravitreal
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黄斑水肿玻璃体内注射受孕精的临床疗效观察
目的观察黄斑水肿玻璃体内注射孔柏注射液治疗视网膜分支静脉阻塞的疗效。方法回顾性分析2018年1月至2018年12月33例视网膜分支静脉闭塞(BRVO-ME)继发性黄斑水肿患者33只眼的资料。随访时间3个月。结果BCVA(logMAR)在注射后1、2、3个月均有改善,注射前与注射后各时间点差异均有统计学意义(Z=4.948、4.642、4.305,P=0.000、0.000、0.000)。注射后1、2、3个月中央黄斑视网膜厚度(CMT)下降,差异均有统计学意义(Z=4.315、4.404、4.387,P=0.000、0.000、0.000)。结论黄斑水肿继发性视网膜分支静脉阻塞玻璃体内注射可在短时间内改善视力,减轻黄斑水肿。关键词:闭塞,静脉,视网膜;黄斑水肿;概念,注射,玻璃体内
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