Research Protocol: Prehabilitation for Holmium Laser Enucleation of the Prostate (HoLEP)

Mubariz Mahmood, D. Cottam, Momen Sid Ahmed, N. Nkwam, T. Rampal
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Abstract

Surgery causes a physiological and psychological stress response which can lead to a decline in functional capacity (1). The adoption of prehabilitation into existing pathways can improve postoperative outcomes. HoLEP (Holmium laser enucleation of the prostate) is a minimally invasive surgical treatment for men with benign prostatic hyperplasia. We aim to assess the feasibility of providing multimodal prehabilitation to patients with an ASA score of 2 or more. The prehabilitation interventions include supervised cardiopulmonary exercise, muscle conditioning, dietary/lifestyle advice and exploration of psychosocial needs. Patients will also receive a medication review by a specialist pharmacist. Compliance is to be assessed with a phonecall 2 weeks into the program and 6 weeks post procedure. Viability of the project will be determined by the ability of the organisation to deliver and sustain the program. The data to be collected will include project costs, time spent, patient satisfaction, length of stay, early and later surgical complications and daycase rate. This project will assess feasibility of perioperative optimisation programmes for non-oncology surgical pathways for maximal patient benefit.
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研究方案:钬激光前列腺摘除(HoLEP)的预康复
手术引起生理和心理应激反应,可导致功能能力下降(1)。在现有通路中采用预适应可以改善术后结果。HoLEP(钬激光前列腺摘除)是一种治疗男性良性前列腺增生的微创手术。我们的目的是评估为ASA评分为2分或以上的患者提供多模式预适应的可行性。康复干预措施包括有监督的心肺运动、肌肉调理、饮食/生活方式建议和探索心理社会需求。患者还将接受专业药剂师的药物审查。依从性将在项目开始2周和程序结束后6周通过电话进行评估。项目的可行性将由组织交付和维持项目的能力决定。收集的数据将包括项目成本、花费的时间、患者满意度、住院时间、早期和晚期手术并发症以及日病例率。该项目将评估非肿瘤手术途径围手术期优化方案的可行性,以获得最大的患者利益。
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