{"title":"Biodegradable polyphosphazene – hydroxyapatite composites for bone tissue engineering","authors":"A. Subash, Abina Basanth, B. Kandasubramanian","doi":"10.1080/00914037.2022.2082426","DOIUrl":null,"url":null,"abstract":"Abstract The venture to fabricate potential and functional bone regeneration, annihilating the health complexities in conventional bone grafting, made Bone tissue engineering (BTE), which facilitates meticulous control of the spatial and temporal dissemination of cells and extracellular matrix (ECM), receive incredible consideration in the past few years. Ascribable to their exceptional properties, polymers have gotten significant attention as one of the prominent classes of biomaterials for BTE. The compatible mechanical properties, biocompatibility, bioactivity, and biodegradability of polyphosphazene/hydroxyapatite composite made them candidates for functional bone regeneration. This review demonstrates the synthesis, properties, and application of polyphosphazenes, hydroxyapatite, and composite biomaterial for BTE. Graphical Abstract","PeriodicalId":14203,"journal":{"name":"International Journal of Polymeric Materials and Polymeric Biomaterials","volume":"19 1","pages":"1093 - 1111"},"PeriodicalIF":2.5000,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Polymeric Materials and Polymeric Biomaterials","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1080/00914037.2022.2082426","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 5
Abstract
Abstract The venture to fabricate potential and functional bone regeneration, annihilating the health complexities in conventional bone grafting, made Bone tissue engineering (BTE), which facilitates meticulous control of the spatial and temporal dissemination of cells and extracellular matrix (ECM), receive incredible consideration in the past few years. Ascribable to their exceptional properties, polymers have gotten significant attention as one of the prominent classes of biomaterials for BTE. The compatible mechanical properties, biocompatibility, bioactivity, and biodegradability of polyphosphazene/hydroxyapatite composite made them candidates for functional bone regeneration. This review demonstrates the synthesis, properties, and application of polyphosphazenes, hydroxyapatite, and composite biomaterial for BTE. Graphical Abstract
期刊介绍：
International Journal of Polymeric Materials and Polymeric Biomaterials is the official publication of the International Society for Biomedical Polymers and Polymeric Biomaterials (ISBPPB). This journal provides a forum for the publication of peer-reviewed, English language articles and select reviews on all aspects of polymeric materials and biomedical polymers. Being interdisciplinary in nature, this journal publishes extensive contributions in the areas of encapsulation and controlled release technologies to address innovation needs as well.
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