Cicatricial pemphigoid with laryngeal involvement

C. Silva, Anna Caroline Rodrigues de Souza Matos, Ana Carla Albuquerque dos Santos, Teresa Nogueira, Viviane Carvalho da Silva
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Abstract

Cicatricial pemphigoid is an uncommon chronic autoimmune inflammatory disease that affects predominantly the mucous membranes. The precise cause of this condition is yet to be fully identified, as well as the mechanism behind the commonly observed subepithelial blistering. This manuscript reports a case of cicatricial pemphigoid with laryngeal involvement, which is a rare manifestation of this also uncommon disease. The patient underwent surgery and specimens were submitted to histopathological examination and immunofluorescence assays, and both ultimately indicated cicatricial
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瘢痕性类天疱疮伴喉部受累
瘢痕性类天疱疮是一种罕见的慢性自身免疫性炎症性疾病,主要影响粘膜。这种情况的确切原因尚未完全确定,以及背后的机制通常观察到的上皮下起泡。本文报告一例瘢痕性类天疱疮伴喉部受累,这是一种罕见的表现,也是罕见的疾病。患者接受了手术,并将标本提交给组织病理学检查和免疫荧光分析,最终均显示瘢痕
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