Canine Wharton's Jelly Derived Mesenchymal Stem Cells Isolation

Ioan Groza, Raul Alexandru Pop, Mihai Cenariu, Simona Ciupe, Emoke Pall
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引用次数: 2

Abstract

Mesenchymal stem cells (MSCs) represent an attractive source of cells for cell therapy in veterinary medicine. Recent interest in stem cell biology and its therapeutic potential has led to search for accessible new sources of stem cells. Wharton‘s Jelly-derived mesenchymal stem cells are multipotent with specific potential to differentiate into multiple lineages.

The aim of our study was the isolation, characterization and multilineage differentiation of Wharton‘s Jelly derived mesenchymal stem cells obtained from canine umbilical cord following Caesarean section.

Our data confirmed that the isolated and cultivated mesenchymal stem cells have multipotent based on specific surface antigen expressing and differentiation capacity.

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犬华顿果冻衍生间充质干细胞的分离
间充质干细胞(MSCs)是兽医学细胞治疗中一个有吸引力的细胞来源。最近对干细胞生物学及其治疗潜力的兴趣促使人们寻找可获得的干细胞新来源。沃顿的果冻来源的间充质干细胞是多能的,具有分化成多种谱系的特定潜力。本研究的目的是分离、表征和多系分化从剖腹产后犬脐带获得的Wharton’s Jelly间充质干细胞。我们的数据证实了分离和培养的间充质干细胞具有基于特异性表面抗原表达和分化能力的多能性。
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