Large highly mobile complex ascending aortic atheroma causing left middle cerebral artery stroke in patient without any history of cardiac disease.

Kinjan P Patel, P. Farjo, Ahmed Almustafa, J. Mills
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Abstract

Introduction: A complex atheroma of the aortic arch puts a patient at risk for an embolic stroke. We present a patient with no cardiac history who came with acute stroke-like symptoms from a large, complex aortic atheroma. Case presentation: A 60-yearold woman with known thoracic aortic aneurysm presented with acute right-sided weakness. An MRI of the brain showed a left middle cerebral artery (MCA) embolic stroke. A CT angiogram (CTA) showed the known, stable thoracic aneurysm and concern for type A aortic dissection. Later gated CT scan revealed a focal filling defect in the proximal aortic arch, compatible with a floating thrombus. A transesophageal echocardiogram (TEE) then demonstrated a 18mm by 14mm, highly mobile atheroma in this area. Specialty team concluded that the stroke was due to the atheroma and suggested anticoagulation and statin therapy. Discussion: A large and mobile aortic atheromas are recognized as a potential cause of embolic events in the elderly population. These patients will benefit from an anticoagulation and statin therapy to reduce the risk of stroke recurrence. Conclusion: A complex aortic atheroma is likely an independent risk factor for embolic stroke and may be an indication for prophylactic anticoagulation and statin therapy.
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无心脏病史的患者出现大的、高度移动的复杂升主动脉粥样硬化,导致左大脑中动脉卒中。
主动脉弓复杂的动脉粥样硬化使患者有栓塞性中风的危险。我们报告了一个没有心脏病史的病人,他从一个大而复杂的主动脉粥样硬化中出现了急性卒中样症状。病例介绍:一名60岁女性,已知患有胸主动脉瘤,表现为急性右侧无力。脑部核磁共振显示左大脑中动脉栓塞性中风。CT血管造影(CTA)显示已知的,稳定的胸动脉瘤,并关注A型主动脉夹层。随后的门控CT扫描显示主动脉弓近端有局灶性充盈缺损,并伴有漂浮血栓。经食管超声心动图(TEE)显示该区域有一个18mm × 14mm高流动性的动脉粥样硬化。专家小组认为中风是由动脉粥样硬化引起的,建议抗凝和他汀类药物治疗。讨论:大而可移动的主动脉粥样硬化被认为是老年人栓塞事件的潜在原因。这些患者将受益于抗凝治疗和他汀类药物治疗,以降低卒中复发的风险。结论:复杂的主动脉粥样硬化可能是栓塞性卒中的独立危险因素,可能是预防性抗凝和他汀类药物治疗的适应症。
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