The Possible Effects of Green Coffee Bean Extract on Progression of Experimental Diabetes in Different Organs; A Review Article

D. Abdel Mohsen, Ahmed M. A. Akabawy, Ahmed Abdemoneim, Hatem K. Amin
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Abstract

Green coffee bean water extract consumption has been stated to have a contrary association with type 2 diabetes and metabolic syndrome. Chlorogenic acid (CGA), an important biologically active dietary polyphenol, is produced by certain plant species and is a major component of coffee. Reduction in the risk of a variety of diseases following CGA consumption has been mentioned in recent basic and clinical research studies. This systematic review discusses in vivo animal and human studies of the physiological and biochemical effects of CGA on biomarkers of diabetic complication and the possible alterations produced by the administration of different doses of green coffee on biomarkers related to renal, testicular, and neurological antioxidant systems.
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绿咖啡豆提取物对实验性糖尿病不同脏器进展的可能影响综述文章
绿咖啡豆水提取物的摄入与2型糖尿病和代谢综合征有相反的关系。绿原酸(CGA)是一种重要的生物活性膳食多酚,由某些植物产生,是咖啡的主要成分。在最近的基础和临床研究中都提到了食用CGA可降低多种疾病的风险。本系统综述讨论了CGA对糖尿病并发症生物标志物的生理生化作用的体内动物和人体研究,以及不同剂量的绿咖啡对肾脏、睾丸和神经抗氧化系统相关生物标志物可能产生的改变。
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