Association between thrombocytopenia and mild infection of COVID-19 patients

A. Yameny
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引用次数: 3

Abstract

Ahmed A. Yameny (Email: dr.ahmedyameny@yahoo.com) Tel: (002)01222708665, (002)01002112248 DOI: 10.21608/jbaar.2021.200859 Abstract: Background: Thrombocytopenia is a common manifestation and also an indicator of poor prognosis of SARS, MERS, and COVID-19 according to previous researches, Some studies have found a relationship between thrombocytopenia and the severity of the COVID-19 and related mortality. Patients and methods: This study included 504 out hospitalized patients with confirmed COVID-19 infection in Alexandria, Egypt, these study subjects were randomly selected irrespective of the age group and both genders were included, EDTA blood sample was collected for performing complete blood count and platelet count (Diagon D-cell 60 hematology analyzer Europe-Diagon Ltd. Hungary). Results: The present study included patients aged from14 years to 75 years mean age was 44.5 ±30.5 who were confirmed to have Covid-19 based on real-time reverse transcriptionpolymerase chain reaction, the female gender was more frequent (n=280, 55.6%) than Male gender (n=224, 44.4%). This study reveals a normal platelet count in 456 patients (90.5%), and a mild low platelet count of 140150× 10/L in 48 patients(9.5%), with a p-value, is 0.415 which is more than 0.05 not significant. And no patients in this studied group recorded platelet count less than 140× 10/L. Conclusion: Platelet was not a significant biomarker for COVID-19 diagnosis or prognosis in out-hospitalized patients (Outpatients and patients under home observation).
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血小板减少症与COVID-19患者轻度感染的关系
摘要:背景:根据以往的研究,血小板减少是SARS、MERS和COVID-19的常见表现,也是预后不良的一个指标,一些研究发现血小板减少与COVID-19的严重程度和相关死亡率有关。患者和方法:本研究纳入埃及亚历山大市确诊COVID-19感染的住院患者504例,研究对象随机选取,不分年龄组和性别,采集EDTA血样进行全血计数和血小板计数(Diagon D-cell 60血液分析仪Europe-Diagon Ltd)。匈牙利)。结果:本组患者年龄14 ~ 75岁,平均年龄44.5±30.5岁,均经实时逆转录聚合酶链反应确诊为Covid-19,其中女性(280例,55.6%)多于男性(224例,44.4%)。本研究发现456例患者血小板计数正常(90.5%),48例患者血小板计数轻度低(140150x10 /L) (9.5%), p值为0.415,p值大于0.05无统计学意义。本组患者血小板计数均未低于140× 10/L。结论:血小板不是门诊患者(门诊患者和居家观察患者)COVID-19诊断和预后的重要生物标志物。
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