Bariatric surgery in obese older people: useful or not?

Susan Reijntjes, A. Viljoen, A. Wierzbicki, T. Hardman
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引用次数: 2

Abstract

ObjectiveThe aim of this study was to determine whether older (≥65 years) obese people would benefit from bariatric surgery, considering the prevalence of multiple comorbidities and frailty in this group. MethodsA PubMed search was carried out for studies on the use of bariatric surgery in older obese people published in the database from 1980 to the present (August 2014). ResultsA total of 244 citations were obtained on searching; 182 of these publications were selected for manual checking and 10 studies were identified as containing useable data on this patient cohort. Published data were available for efficacy in 641 patients. Substantial improvement was observed in diabetes (76%), hypertension (68%) and sleep apnoea (67%) following bariatric surgery. Laparoscopic adjustable gastric banding (n=456) was the most frequently reported procedure. Similar findings but with greater weight loss and fewer complications were found in the small numbers of patients undergoing other procedures. Data from four large registry studies (n=6837) showed mortality and complications associated with bariatric surgery to be increased in older compared with younger people especially in those undergoing gastric bypass surgery. The elderly had longer hospital stays, and patients with cardiac, pulmonary or renal comorbidities generally had a worse prognosis. ConclusionBariatric surgery in older people is effective in reducing complications of obesity, but is also associated with increased rates of complications compared with those seen in younger patients. The few reported studies in the elderly are retrospective, generally small, primarily describe findings of laparoscopic adjustable gastric banding as the surgical intervention option and lack long-term follow-up. More trials and registry data, especially for sleeve gastrectomy and gastric bypass, are required to better address the utility of bariatric surgery in the elderly and to define long-term clinical outcomes.
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肥胖老年人的减肥手术:有用还是没用?
本研究的目的是确定老年(≥65岁)肥胖者是否会从减肥手术中获益,考虑到该组中多种合并症和虚弱的患病率。方法通过PubMed检索数据库中自1980年至今(2014年8月)发表的关于老年肥胖患者使用减肥手术的研究。结果检索到文献共244篇;其中182份出版物被选中进行人工检查,其中10项研究被确定为包含该患者队列的可用数据。已发表的641例患者的疗效数据。减肥手术后,糖尿病(76%)、高血压(68%)和睡眠呼吸暂停(67%)均有显著改善。腹腔镜可调节胃束带(n=456)是最常报道的手术。在少数接受其他手术的患者中发现了类似的结果,但体重减轻幅度更大,并发症更少。来自四项大型登记研究(n=6837)的数据显示,与年轻人相比,老年人与减肥手术相关的死亡率和并发症增加,特别是在接受胃分流手术的人群中。老年人住院时间较长,有心脏、肺部或肾脏合并症的患者通常预后较差。结论老年人减肥手术可有效减少肥胖并发症,但与年轻患者相比,其并发症发生率也有所增加。少数报道的老年人研究是回顾性的,通常规模较小,主要描述了腹腔镜可调节胃束带作为手术干预选择的结果,缺乏长期随访。需要更多的试验和注册数据,特别是袖式胃切除术和胃旁路手术,以更好地解决减肥手术在老年人中的效用,并确定长期临床结果。
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