MULTI-DRUG RESISTANT UROPATHOGENS ISOLATED FROM MID STREAM URINE SAMPLES

N. Regmi, Sonali Kafle, R. Paudyal
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引用次数: 3

Abstract

A frequent and consistent evaluation of the prevalence, etiologic agents and predisposing factors of urinary tract infection (UTI) is necessary in developing country like Nepal to reduce its severe consequences. A regular and routine monitoring of multidrug resistant (MDR) clinical isolates is essential in laboratory practice. Five hundred and ninety one mid stream urine samples were collected from Bharosa Hospital of Kathmandu and a semi-quantitative method was used to determine the frequency of MDR uropathogens in the urine samples. Isolation, identification and antimicrobial susceptibility of isolated bacteria were done by standard microbiological procedure. From the total samples, 161 samples were found to be positive for UTI (27.24 %). Among these bacterial isolates, 57.14 % were found to be MDR. Nitrofurantoin, amikacin and ceftriaxone were found to be the most effective antibiotics against uropathogens.
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从中游尿样中分离出多重耐药尿路病原体
在尼泊尔这样的发展中国家,有必要对尿路感染的患病率、病因和易感因素进行频繁和一致的评估,以减少其严重后果。在实验室实践中,对耐多药临床分离株进行定期和常规监测至关重要。从加德满都巴罗萨医院采集了591份中流尿样,采用半定量方法测定尿样中耐多药尿路病原体的频率。采用标准微生物学程序对分离菌进行分离鉴定和药敏试验。其中,尿路感染阳性161例(27.24%)。其中57.14%为耐多药。呋喃妥因、阿米卡星和头孢曲松是治疗泌尿系病原体最有效的抗生素。
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