Antioksidan ve Üreaz Enzim İnhibitörü Olarak Siyah Çay İşleme Atığındaki Kateşinleri İçeren Bazı Azo Bileşikleri

Cihan Kantar, Zeliha Er, Nimet Baltaş, Selami Şaşmaz
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Abstract

Although various azo compounds containing some natural origin catechins had been synthesized and determined their dyeing properties for various textile products, azo compounds containing black tea waste catechins and their antioxidant capacity and urease enzyme inhibition were not investigated until this study. The urease enzyme is the most important enzyme that allows the bacteria Helicobacter pylori, which is considered the main factor of stomach cancer, to live in the stomach. Inhibition of this enzyme is very important for the treatment of Helicobacter pylori infection. It has been known that catechin extracts of natural origin inhibit the urease enzyme of Helicobacter pylori from literature. Black tea processing waste is a residue that is separated from the sieves during tea processing and has no economic value. The transformation of this residue into products that produce added value is very important because it contains many chemicals contained in the tea plant. In this study, some azo compounds containing black tea processing waste catechins were synthesized and investigated their antioxidant capacity, urease enzyme inhibition properties.
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虽然已经合成了多种含有天然来源儿茶素的偶氮化合物,并测定了它们对各种纺织品的染色性能,但直到本研究才对含有红茶废儿茶素的偶氮化合物及其抗氧化能力和脲酶抑制能力进行了研究。被认为是导致胃癌的主要因素——幽门螺杆菌能够在胃中生存的最重要的酶就是脲酶。抑制该酶对治疗幽门螺杆菌感染非常重要。从文献上已经知道,天然来源的儿茶素提取物抑制幽门螺杆菌的脲酶。红茶加工废料是茶叶加工过程中从筛子中分离出来的残渣,没有经济价值。将这些残留物转化为产生附加值的产品是非常重要的,因为它含有茶树中含有的许多化学物质。本文合成了几种含红茶加工废儿茶素的偶氮化合物,并对其抗氧化能力、脲酶抑制性能进行了研究。
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